Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222879 | 0.79 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL2127579 | 0.74 | CYP3A4 (0.64) | CYP3A4 | |
| SCHEMBL1542551 | 0.74 | CYP3A4 (0.64) | CYP3A4 | |
| SCHEMBL1349044 | 0.74 | CYP3A4 (0.38) | CYP3A4 | |
| SCHEMBL1349042 | 0.74 | CYP3A4 (0.38) | CYP3A4 | |
| SCHEMBL1543266 | 0.67 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL2127645 | 0.67 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL2127641 | 0.67 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL1542773 | 0.64 | CYP3A4 (0.68) | CYP3A4 | |
| SCHEMBL2128593 | 0.63 | CYP3A4 (0.70) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480533-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| WO-2011033045-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-24 | — | — | WO | disclosed |