Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162556 | 0.90 | AKR1C1 (0.47) | MAPTSMN1; SMN2L3MBTL1POLBMEN1 | |
| SCHEMBL8162561 | 0.90 | AKR1C1 (0.47) | MAPTSMN1; SMN2L3MBTL1POLBMEN1 | |
| SCHEMBL8214861 | 0.88 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2L3MBTL1POLBMEN1 | |
| SCHEMBL8215241 | 0.82 | POLB (0.50) | MAPTSMN1; SMN2L3MBTL1POLBMEN1 | |
| SCHEMBL8215469 | 0.79 | GSK3B (0.41) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL10765334 | 0.78 | AKR1C1 (0.44) | MAPTMEN1KMT2AALDH1A1PTPN1 | |
| SCHEMBL10765330 | 0.78 | AKR1C1 (0.44) | MAPTMEN1KMT2AALDH1A1PTPN1 | |
| SCHEMBL8894614 | 0.76 | POLB (0.57) | MAPTSMN1; SMN2L3MBTL1POLBMEN1 | |
| SCHEMBL8220602 | 0.76 | KMT2A (0.39) | MAPTSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL23079029 | 0.75 | ERCC5 (0.45) | SMN1; SMN2MEN1KMT2AHPGDERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106908-A | OPTICAL APPARATUS WITH LIQUID CRYSTAL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2000-08-22 | — | — | US | disclosed |