SCHEMBL821985

SCHEMBL821985

NCCC(N)=O.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82768 0.96
Water SCHEMBL27884819 0.93
SCHEMBL821969 0.93
Hydrochloric Acid SCHEMBL9998745 0.93
Hydrochloric Acid SCHEMBL793439 0.93
SCHEMBL16447295 0.93
SCHEMBL251118 0.93
Phosphine SCHEMBL31031792 0.93
Ammonia Solution, Strong SCHEMBL13571350 0.93
SCHEMBL9725 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275872-A1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE LONZA LTD (CH) 2011-11-10 US claimed
EP-2260014-B1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE LONZA AG (CH) 2011-09-28 EP claimed
EP-2260014-A1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE Lonza Ltd. (CH) 2010-12-15 EP claimed
WO-2009118179-A1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE LONZA LTD (CH) 2009-10-01 WO claimed
EP-1807436-B1 HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) AND USES THEREOF INTEZYNE TECHNOLOGIES INC (US) 2014-06-18 EP disclosed
EP-2502941-A1 Heterobifunctional poly (ethylene glycol) and uses thereof Intezyne Technologies Inc. (US) 2012-09-26 EP disclosed
US-20110275872-A1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE LONZA LTD (CH) 2011-11-10 US disclosed
EP-2260014-B1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE LONZA AG (CH) 2011-09-28 EP disclosed
EP-2260014-A1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE Lonza Ltd. (CH) 2010-12-15 EP disclosed
US-7612153-B2 conjugate polymer drugs; endcapped polyethers; nontoxic, biocompatible, non-immunogenic, soluble in water and other solvents INTEZYNE TECHNOLOGIES, INC. (US) 2009-11-03 US disclosed
WO-2009118179-A1 PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE LONZA LTD (CH) 2009-10-01 WO disclosed
EP-1807436-A2 HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) AND USES THEREOF Intezyne Technologies Incorporated (US) 2007-07-18 EP disclosed
US-20060142506-A1 Heterobifunctional poly(ethylene glycol) and uses thereof INTEZYNE TECHNOLOGIES, INC. 2006-06-29 US disclosed
WO-2006047419-A2 HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) AND USES THEREOF INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2006-05-04 WO disclosed
US-5162562-A Preparation of metallated and substituted alkynes AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-11-10 US disclosed
US-5062998-A Preparation of metallated and substituted alkynes AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-11-05 US disclosed