Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 3/20 | 0.36 |
| ▸ | CPT2 | P23786 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628529 | 0.91 | GRM5 (0.43) | CPT1ACPT2USP30GRM5 | |
| SCHEMBL8225979 | 0.90 | CPT1A (0.36) | CPT1ACPT2GRM5 | |
| SCHEMBL4078261 | 0.89 | GRM5 (0.39) | CPT1ACPT2USP30GRM5 | |
| SCHEMBL4078277 | 0.89 | GRM5 (0.39) | CPT1ACPT2USP30GRM5 | |
| SCHEMBL8230979 | 0.88 | GRM5 (0.36) | CPT1ACPT2GRM5 | |
| SCHEMBL5631797 | 0.86 | USP30 (0.40) | CPT1ACPT2USP30GRM5KCNH2 | |
| SCHEMBL5631775 | 0.86 | USP30 (0.40) | CPT1ACPT2USP30GRM5KCNH2 | |
| SCHEMBL4377245 | 0.81 | GRM5 (0.45) | CPT1ACPT2GRM5 | |
| SCHEMBL4076476 | 0.79 | GRM5 (0.40) | CPT1ACPT2GRM5 | |
| SCHEMBL4076468 | 0.79 | GRM5 (0.40) | CPT1ACPT2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130821-A2 | MGLUR5 MODULATORS II | ASTRAZENECA AB (SE) | 2007-11-15 | — | — | WO | disclosed |