Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 20/20 | 1.00 |
| ▸ | MAPK12 | P53778 | 20/20 | 1.00 |
| ▸ | MAPK11 | Q15759 | 20/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL4585315 | 0.84 | MAPK14 (0.72) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4915298 | 0.84 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4908525 | 0.82 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4918512 | 0.81 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6420880 | 0.80 | MAPK13 (0.75) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4593758 | 0.79 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7611282 | 0.79 | MAPK14 (0.65) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6421005 | 0.79 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4592699 | 0.77 | MAPK14 (0.78) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL15830688 | 0.76 | CSNK1D (0.85) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150557-A | REACTING COMPOUND CONTAINING SECONDARY AMIDE GROUPS WITH BENZENESULFINIC ACID OR ITS DERIVATIVE IN PRESENCE OF ACID CATALYST | SMITHKLINE BEECHAM CORPORATION (US) | 2000-11-21 | — | — | US | disclosed |