Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 15/20 | 0.65 |
| ▸ | FAP | Q12884 | 13/20 | 0.65 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.65 |
| ▸ | PREP | P48147 | 5/20 | 0.55 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222415 | 0.94 | DPP4 (0.61) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL21746960 | 0.82 | DPP4 (0.88) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL21746959 | 0.82 | DPP4 (0.88) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8229507 | 0.81 | DPP4 (0.97) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL21746962 | 0.81 | DPP4 (0.91) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL21746963 | 0.81 | DPP4 (0.91) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL12340747 | 0.79 | DPP4 (1.00) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL21746923 | 0.79 | DPP4 (1.00) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8231049 | 0.79 | DPP4 (1.00) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8229510 | 0.76 | DPP4 (0.76) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123686-A2 | DPP INHIBITORS AND USES THEREOF | POINT THERAPEUTICS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |