Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | REN | P00797 | 7/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | CTSE | P14091 | 2/20 | 0.45 |
| ▸ | PGC | P20142 | 2/20 | 0.45 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.40 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919455 | 1.00 | GBA1 (0.54) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL8228607 | 0.84 | HTR2C (0.53) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL8228603 | 0.80 | GBA1 (0.49) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL3911891 | 0.80 | GBA1 (0.49) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL8222704 | 0.79 | GBA1 (0.51) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL3913849 | 0.79 | GBA1 (0.51) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL3910632 | 0.79 | GBA1 (0.54) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL8223739 | 0.79 | GBA1 (0.54) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL3910631 | 0.78 | GBA1 (0.50) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL3913840 | 0.78 | USP2 (0.50) | GBA1RENCTSDCTSEPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140980-A1 | PYRROLIDINE DERIVATIVES USEFUL AS BACE INHIBITORS | NOVARTIS AG (CH) | 2007-12-13 | — | — | WO | disclosed |