Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.64 |
| ▸ | BACE2 | Q9Y5Z0 | 14/20 | 0.51 |
| ▸ | CTSD | P07339 | 12/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8224530 | 0.94 | BACE1 (0.69) | BACE1BACE2CTSDAPP | |
| Acetic Acid SCHEMBL4888178 | 0.90 | BACE1 (0.65) | BACE1BACE2CTSDAPP | |
| SCHEMBL8225886 | 0.84 | BACE1 (0.60) | BACE1BACE2CTSDAPP | |
| SCHEMBL8226747 | 0.82 | BACE1 (0.62) | BACE1BACE2CTSDAPP | |
| SCHEMBL8221934 | 0.82 | BACE1 (0.80) | BACE1BACE2CTSDAPP | |
| Hydrochloric Acid SCHEMBL4892607 | 0.81 | BACE1 (0.79) | BACE1BACE2CTSDAPP | |
| SCHEMBL8218325 | 0.80 | BACE1 (0.65) | BACE1BACE2CTSDAPP | |
| SCHEMBL4884566 | 0.80 | BACE1 (0.76) | BACE1BACE2CTSDAPP | |
| SCHEMBL4887766 | 0.79 | BACE1 (0.63) | BACE1BACE2CTSDAPP | |
| SCHEMBL4884550 | 0.79 | BACE1 (0.88) | BACE1BACE2CTSDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145569-A1 | AMINO-IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA | ASTRAZENECA AB (SE) | 2007-12-21 | — | — | WO | disclosed |