SCHEMBL8223441

SCHEMBL8223441

C[C@@H]1CCSC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193257 1.00
SCHEMBL13295810 1.00
SCHEMBL20819984 0.89
SCHEMBL11917534 0.85
Cyclohexene SCHEMBL10946559 0.83
SCHEMBL13636956 0.81
SCHEMBL19302097 0.81
SCHEMBL762700 0.81
SCHEMBL10150513 0.79
SCHEMBL11228506 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229091-A1 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE CODEXIS INC (US) 2024-07-11 US disclosed
WO-2020135771-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2020-07-02 WO disclosed
US-20180187223-A1 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2018-07-05 US disclosed
US-20180179185-A1 AMINO COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2018-06-28 US disclosed
US-9932615-B2 Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane CODEXIS, INC. (US) 2018-04-03 US disclosed
US-20170320860-A1 HETEROCYCLIC TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC. 2017-11-09 US disclosed
US-20160289717-A1 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2016-10-06 US disclosed
US-9394552-B2 Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane CODEXIS, INC. (US) 2016-07-19 US disclosed
US-20150125910-A1 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2015-05-07 US disclosed
US-8962285-B2 Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane CODEXIS, INC. (US) 2015-02-24 US disclosed
US-8513162-B2 Halogen-containing organosulfur compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-20 US disclosed
EP-2586596-A1 THREE-DIMENSIONAL POLYMER-METAL COMPOSITE MICROSTRUCTURE AND METHOD FOR PRODUCING SAME Japan Science and Technology Agency (JP) 2013-05-01 EP disclosed
EP-2520568-A1 Spirocyclic nitriles as inhibitors of protease SANOFI (FR) 2012-11-07 EP disclosed
US-20120276599-A1 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE PFIZER, INC. (US) 2012-11-01 US disclosed
US-8227229-B2 Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane CODEXIS, INC. (US) 2012-07-24 US disclosed
US-20110217754-A1 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE CODEXIS, INC. (US) 2011-09-08 US disclosed
WO-2010074327-A1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUNDS AND USE THEREOF FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-01 WO disclosed
US-20100081693-A1 THIADIAZOLE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-01 US disclosed
WO-2007137738-A1 SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS SANOFI-AVENTIS (DE) 2007-12-06 WO disclosed