Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223994 | 1.00 | KDM4E (0.45) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL28359895 | 0.90 | KDM4E (0.41) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL9166069 | 0.87 | KDM4E (0.51) | KDM4ELMNATRPA1NFE2L2CYP11B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28445804 | 0.83 | KDM1A (0.46) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL4165025 | 0.82 | KDM4E (0.46) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL4165023 | 0.82 | KDM4E (0.46) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL9166072 | 0.82 | ALK (0.41) | KDM4ELMNACYP1A2POLBCCR1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28562270 | 0.81 | KDM4E (0.67) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL4155559 | 0.81 | KDM1A (0.47) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL2773355 | 0.81 | KDM1A (0.47) | KDM4ELMNACYP1A2POLBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073755-A2 | IMPROVED PRESSURE SENSOR | CANPOLAR EAST INC. (CA) | 2000-12-07 | — | — | WO | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |