⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12091637 | 0.82 | — | — | |
| SCHEMBL2640818 | 0.80 | — | — | |
| SCHEMBL15721587 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL21078022 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL20049728 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL18602569 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL21086937 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL20648013 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL25951118 | 0.78 | EPHX1 (0.56) | — | |
| SCHEMBL15429197 | 0.78 | MCL1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114229871-B | Method for improving stability of evaporation system of byproduct brine of ketone hydrazine hydrate | 宜宾海丰和锐有限公司 | 2024-02-13 | — | — | CN | disclosed |
| US-11672787-B2 | Compounds as mPGES-1 inhibitors | KHONDRION IP B.V. (NL) | 2023-06-13 | — | — | US | disclosed |
| CN-114574090-B | Anti-dazzle and anti-scratch functional film for display and preparation method and application thereof | 宁波集科威视讯有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-216687790-U | Ketone method hydrazine hydrate byproduct salt water evaporation mother liquor processing system | 宜宾海丰和锐有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114574090-A | Anti-dazzle and anti-scratch functional film for display and preparation method and application thereof | 宁波集科威视讯有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114229871-A | Method for improving stability of ketone method hydrazine hydrate byproduct salt water evaporation system | 宜宾海丰和锐有限公司 | 2022-03-25 | — | — | CN | disclosed |
| WO-2021124222-A1 | PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021104710-A1 | METHOD FOR THE DECOLORIZATION OF KERATIN MATERIAL THAT HAS BEEN DYED USING AN AMINO SILICONE AND A PIGMENT | HENKEL AG & CO. KGAA (DE) | 2021-06-03 | — | — | WO | disclosed |
| WO-2019042267-A1 | PYRROLE-2-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATIONS THEREOF | 中国医学科学院药物研究所 | 2019-03-07 | — | — | WO | disclosed |
| US-9923154-B2 | Organic electroluminescent element, lighting device, and display device | Konica Minolta, Inc. (JP) | 2018-03-20 | — | — | US | disclosed |
| WO-2017124087-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-07-20 | — | — | WO | disclosed |
| WO-2017060432-A1 | NOVEL COMPOUNDS FOR TREATING MITOCHONDRIAL DISEASE | KHONDRION IP B.V. (NL) | 2017-04-13 | — | — | WO | disclosed |
| US-9388156-B2 | Chromanyl derivatives for treating mitochondrial disease | Khondiron IP B.V. (NL) | 2016-07-12 | — | — | US | disclosed |
| US-9388156-B2 | Chromanyl derivatives for treating mitochondrial disease | Khondiron IP B.V. (NL) | 2016-07-12 | — | — | US | disclosed |
| US-20150166501-A1 | CHROMANYL DERIVATIVES FOR TREATING MITOCHONDRIAL DISEASE | KHONDRION IP B.V. (NL) | 2015-06-18 | — | — | US | disclosed |
| US-20150166501-A1 | CHROMANYL DERIVATIVES FOR TREATING MITOCHONDRIAL DISEASE | KHONDRION IP B.V. (NL) | 2015-06-18 | — | — | US | disclosed |
| CN-104529049-A | Treatment method for using ketazine process hydrazine hydrate brine waste in ion exchange membrane electrolysis | YIBIN TIANYUAN GROUP CO LTD | 2015-04-22 | — | — | CN | disclosed |
| WO-2014100719-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2007100374-A9 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TUFTS COLLEGE (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007100374-A2 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2007-09-07 | — | — | WO | disclosed |