Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557060 | 0.92 | CXCR4 (0.61) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL3141446 | 0.84 | TLR8 (0.68) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL3136462 | 0.84 | TLR8 (0.68) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL10833410 | 0.84 | TLR8 (0.68) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL15382597 | 0.84 | TLR8 (0.68) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL14557079 | 0.83 | CXCR4 (0.52) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL3137088 | 0.83 | TLR8 (0.68) | CXCR4TLR8TP53SMN1; SMN2MAPT | |
| SCHEMBL3840545 | 0.81 | TLR8 (0.67) | TLR8TP53SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11196535 | 0.81 | CXCR4 (0.51) | CXCR4TLR8TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL8267652 | 0.81 | CXCR4 (0.49) | CXCR4TLR8TP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134169-A9 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF | NUADA LLC (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2007134169-A2 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF | NUADA, LLC (US) | 2007-11-22 | — | — | WO | disclosed |