SCHEMBL822894

SCHEMBL822894

C=P1(C)Oc2ccccc2-c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11336478 0.78 KDM4E (0.31) KDM4EMAPK1ATM
SCHEMBL25611345 0.76 KDM4E (0.31) KDM4EMAPK1ATM
SCHEMBL822718 0.76 HSP90AA1 (0.33) KDM4EMAPK1ATM
SCHEMBL822893 0.76 HSP90AA1 (0.33) KDM4EMAPK1ATM
SCHEMBL16491434 0.76 HSP90AA1 (0.33) KDM4EMAPK1ATM
SCHEMBL26745090 0.73 KDM4E (0.32) KDM4EMAPK1ATM
SCHEMBL26745124 0.71 KDM4E (0.32) KDM4EMAPK1ATM
SCHEMBL15981888 0.71
SCHEMBL14901051 0.70 KDM4E (0.34) KDM4EMAPK1ATM
SCHEMBL16082355 0.70 HSP90AA1 (0.38) KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2890744-B1 FLAME-RETARDANT BENZOXAZINE-CONTAINING COMPOSITION HENKEL AG & CO KGAA (DE) 2021-02-17 EP disclosed
US-8349224-B2 Melamine phenylphosphonate flame retardant compositions BASF SE Ludwigshafen (DE) 2013-01-08 US disclosed
US-8236881-B2 DOPO flame retardant compositions BASF SE (DE) 2012-08-07 US disclosed
US-20120184635-A1 Flameproof expandable polymerizates Sunpor Kunststoff Ges m.b.H. (AT) 2012-07-19 US disclosed
US-20120095140-A1 DOPO FLAME RETARDANT COMPOSITIONS ROTH MICHAEL (DE) 2012-04-19 US disclosed
US-8101678-B2 DOPO flame retardant compositions BASF SE (DE) 2012-01-24 US disclosed
US-20110266507-A1 MELAMINE PHENYLPHOSPHONATE FLAME RETARDANT COMPOSITIONS BASF SE (DE) 2011-11-03 US disclosed
US-20100234495-A1 DOPO FLAME RETARDANT COMPOSITIONS CIBA CORPORATION (US) 2010-09-16 US disclosed