Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579226 | 0.89 | HDAC1 (0.68) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2206079 | 0.79 | HDAC1 (0.68) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4580057 | 0.78 | HDAC1 (0.74) | HDAC1HDAC2HDAC3 | |
| SCHEMBL8219788 | 0.77 | HDAC1 (0.68) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2209455 | 0.77 | HDAC1 (0.75) | HDAC1HDAC2 | |
| SCHEMBL7934855 | 0.76 | HDAC1 (0.80) | HDAC1HDAC2HDAC3 | |
| SCHEMBL3643999 | 0.75 | HDAC1 (0.72) | HDAC1HDAC2HDAC3 | |
| SCHEMBL1930442 | 0.75 | HDAC1 (0.60) | HDAC1HDAC2 | |
| SCHEMBL4578576 | 0.74 | HDAC1 (0.73) | HDAC1HDAC2 | |
| SCHEMBL8291413 | 0.74 | HDAC1 (0.59) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118137-A1 | BENZAMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-10-18 | — | — | WO | disclosed |