Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 20/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231667 | 0.92 | HDAC1 (0.57) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4577958 | 0.92 | HDAC1 (0.57) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4577585 | 0.85 | HDAC1 (0.63) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4578185 | 0.79 | HDAC1 (0.66) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4579959 | 0.78 | HDAC1 (0.41) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4579710 | 0.78 | HDAC1 (0.64) | HDAC1HDAC2HDAC3 | |
| SCHEMBL1063413 | 0.73 | HDAC1 (0.63) | HDAC1HDAC2HDAC3 | |
| SCHEMBL7938248 | 0.73 | HDAC1 (0.61) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4579949 | 0.72 | HDAC1 (0.41) | HDAC1HDAC2HDAC3 | |
| SCHEMBL13833718 | 0.72 | HDAC1 (1.00) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118137-A1 | BENZAMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-10-18 | — | — | WO | disclosed |