Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | HNF4A | P41235 | 2/20 | 0.81 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.77 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.77 |
| ▸ | LCK | P06239 | 1/20 | 0.71 |
| ▸ | APP | P05067 | 5/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.51 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385358 | 0.89 | PTPN1 (1.00) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL673426 | 0.89 | PTPN1 (1.00) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL30075246 | 0.89 | PTPN1 (1.00) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL8229438 | 0.89 | PTPN1 (0.73) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL7706129 | 0.89 | PTPN1 (0.73) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL23143179 | 0.88 | PTPN1 (0.68) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL7895177 | 0.88 | PTPN1 (0.68) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL30075293 | 0.88 | PTPN1 (0.68) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL6266631 | 0.87 | PTPN1 (1.00) | PTPN1HNF4APTPN2PTPN6LCK | |
| SCHEMBL1048686 | 0.87 | PTPN1 (1.00) | PTPN1HNF4APTPN2PTPN6LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977815-A1 | ALKYL, ALKENYL AND ALKYNYL CHRYSAMINE G DERIVATIVES FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND $i(IN VIVO) IMAGING AND PREVENTION OF AMYLOID DEPOSITION | UNIVERSITY OF PITTSBURGH (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047969-A1 | ALKYL, ALKENYL AND ALKYNYL CHRYSAMINE G DERIVATIVES FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | UNIVERSITY OF PITTSBURGH (US) | 1998-10-29 | — | — | WO | disclosed |