Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550371 | 0.90 | F10 (0.45) | F10GRM1POLBMAPTABCB11 | |
| SCHEMBL8230159 | 0.87 | F10 (0.51) | F10ABCB11F2ST14 | |
| SCHEMBL3617551 | 0.86 | F10 (0.42) | F10GRM1POLBMAPTABCB11 | |
| SCHEMBL13070056 | 0.86 | F10 (0.39) | F10GRM1ABCB11F2ST14 | |
| SCHEMBL8229717 | 0.85 | AHR (0.40) | F10GRM1ABCB11F2ST14 | |
| SCHEMBL8224810 | 0.80 | F10 (0.43) | F10ABCB11F2ST14 | |
| SCHEMBL8230285 | 0.80 | F10 (0.41) | F10GRM1POLBMAPTPARP1 | |
| SCHEMBL13069758 | 0.78 | PARP1 (0.39) | F10GRM1POLBMAPTPARP1 | |
| SCHEMBL3617096 | 0.77 | F10 (0.41) | F10MAPTABCB11F2ST14 | |
| SCHEMBL3985616 | 0.77 | F10 (0.61) | F10ABCB11F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137800-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |