Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17316361 | 0.82 | SSTR5 (0.46) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL29228926 | 0.81 | HIF1A (0.44) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL8225530 | 0.79 | HIF1A (0.44) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL30523664 | 0.78 | HIF1A (0.46) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL20766930 | 0.78 | HIF1A (0.46) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL17316417 | 0.78 | HIF1A (0.41) | HIF1AEPAS1HTR2ASSTR5TRPM8 | |
| SCHEMBL30940046 | 0.78 | HIF1A (0.44) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL27968850 | 0.78 | HIF1A (0.44) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL13156334 | 0.78 | HIF1A (0.44) | HIF1AEPAS1HTR2ASSTR5MAPT | |
| SCHEMBL8194599 | 0.76 | HIF1A (0.48) | HIF1AEPAS1HTR2ASSTR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |