⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643535 | 0.75 | — | — | |
| SCHEMBL4352031 | 0.73 | — | — | |
| SCHEMBL4352028 | 0.73 | — | — | |
| SCHEMBL13772757 | 0.73 | — | — | |
| SCHEMBL1003533 | 0.71 | — | — | |
| SCHEMBL9344159 | 0.71 | — | — | |
| SCHEMBL9344162 | 0.71 | — | — | |
| SCHEMBL13679425 | 0.69 | — | — | |
| SCHEMBL647339 | 0.69 | — | — | |
| SCHEMBL22487756 | 0.69 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067632-B2 | Process to produce prostratin and structural or functional analogs thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-11-29 | — | — | US | disclosed |
| US-20090187046-A1 | Process to Produce Prostratin and Structural or Functional Analogs Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-07-23 | — | — | US | disclosed |