Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 10/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232859 | 0.88 | HPGD (0.47) | HPGDF10TSHR | |
| SCHEMBL8225099 | 0.85 | HPGD (0.47) | HPGDF10TSHR | |
| SCHEMBL8230688 | 0.84 | HPGD (0.47) | HPGDF10TSHRMAPK1 | |
| SCHEMBL3087908 | 0.82 | HPGD (0.53) | HPGDF10TSHRMAPK1 | |
| SCHEMBL1708736 | 0.81 | HPGD (0.52) | HPGDF10TSHRMAPK1 | |
| SCHEMBL3089664 | 0.81 | HPGD (0.52) | HPGDF10TSHRMAPK1 | |
| SCHEMBL4900929 | 0.81 | HPGD (0.43) | HPGDF10TSHR | |
| SCHEMBL8277767 | 0.79 | HPGD (0.49) | HPGDF10TSHRMAPK1 | |
| SCHEMBL1106605 | 0.79 | HPGD (0.49) | HPGDF10TSHRMAPK1 | |
| SCHEMBL1097361 | 0.78 | HPGD (0.47) | HPGDF10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007131179-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-11-15 | — | — | WO | disclosed |