Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579569 | 0.92 | HDAC1 (0.46) | HDAC1HDAC2HDAC3MCHR1HDAC4 | |
| SCHEMBL4579572 | 0.77 | HDAC1 (0.45) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4580210 | 0.76 | HDAC1 (0.50) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4581147 | 0.76 | HDAC1 (0.66) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14155959 | 0.75 | HDAC1 (0.48) | HDAC1HDAC2HDAC3MCHR1HDAC4 | |
| SCHEMBL4579369 | 0.75 | HDAC1 (0.55) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4578077 | 0.75 | HDAC1 (0.59) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4579390 | 0.74 | KDR (0.51) | HDAC1HDAC2HDAC3MCHR1 | |
| SCHEMBL4577896 | 0.74 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4578776 | 0.73 | HDAC1 (0.49) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118137-A1 | BENZAMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-10-18 | — | — | WO | disclosed |