Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230518 | 0.89 | F10 (0.50) | F10ALDH1A1HPGDSMN1; SMN2ACKR3 | |
| SCHEMBL8230566 | 0.84 | F10 (0.68) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL3376377 | 0.84 | F10 (0.74) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL5777469 | 0.84 | F10 (0.74) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL5782623 | 0.83 | F10 (0.76) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL5779422 | 0.83 | F10 (0.73) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL5779855 | 0.83 | F10 (0.73) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL5779069 | 0.83 | F10 (0.68) | F10ALDH1A1HPGDSMN1; SMN2ACKR3 | |
| SCHEMBL5782214 | 0.82 | F10 (0.70) | F10ALDH1A1HPGDSMN1; SMN2DHPS | |
| SCHEMBL5784059 | 0.82 | F10 (0.72) | F10ALDH1A1HPGDSMN1; SMN2DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |