Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.69 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.69 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.66 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.66 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28900354 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL29924037 | 0.98 | SLC1A2 (0.68) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL28900379 | 0.98 | SLC1A2 (0.68) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL28900378 | 0.98 | SLC1A2 (0.68) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL27860274 | 0.98 | SLC1A2 (0.68) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL28900373 | 0.92 | SLC1A2 (0.67) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL28900372 | 0.92 | SLC1A2 (0.67) | GRIK1GRIK2SLC1A2SLC1A1ACE2 | |
| SCHEMBL839403 | 0.84 | SLC1A2 (0.64) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3383446 | 0.84 | SLC1A2 (0.64) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18229129 | 0.84 | SLC1A2 (0.64) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115074404-B | Synthesis method of (2S, 4R) -2-amino-4-methyl nonanoic acid | 吉尔多肽生物制药(大连市)有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115074404-A | Synthesis method of (2R, 4R) -2-amino-4-methylnonanoic acid | 吉尔多肽生物制药(大连市)有限公司 | 2022-09-20 | — | — | CN | disclosed |
| US-6033823-A | Mutated penicillin G acylase genes | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V., (NL) | 2000-03-07 | — | — | US | disclosed |
| EP-0775210-B1 | MUTATED PENICILLIN G ACYLASE GENES | DSM NV (NL) | 2000-02-02 | — | — | EP | disclosed |
| US-5891703-A | Mutated penicillin G acylase genes | GIST-HROCADES (NL) | 1999-04-06 | — | — | US | disclosed |
| US-5695978-A | CULTURE PRODUCT | GIST-BROCADES, N.V. (NL) | 1997-12-09 | — | — | US | disclosed |
| EP-0775210-A1 | MUTATED PENICILLIN G ACYLASE GENES | GIST-BROCADES B.V. (NL) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005318-A1 | MUTATED PENICILLIN G ACYLASE GENES | GIST-BROCADES B.V. (NL) | 1996-02-22 | — | — | WO | disclosed |
| EP-0453047-B1 | Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme | GIST BROCADES NV (NL) | 1995-07-05 | — | — | EP | disclosed |
| US-5168048-A | Genetic engineering of Alcaligenes | GIST-BROCADES NV (NL) | 1992-12-01 | — | — | US | disclosed |
| EP-0453047-A1 | Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme | GIST-BROCADES N.V. (NL) | 1991-10-23 | — | — | EP | disclosed |