Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 15/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.63 |
| ▸ | IGF1R | P08069 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462683 | 0.85 | TNK2 (0.83) | TNK2IGF1R | |
| SCHEMBL397933 | 0.84 | IGF1R (0.82) | TNK2FGFR1IGF1RCYP3A4 | |
| SCHEMBL400047 | 0.82 | IGF1R (0.68) | TNK2IGF1R | |
| SCHEMBL8237190 | 0.81 | TNK2 (0.71) | TNK2FGFR1IGF1R | |
| SCHEMBL401143 | 0.81 | IGF1R (0.61) | TNK2FGFR1IGF1RCYP3A4 | |
| SCHEMBL400491 | 0.81 | IGF1R (0.66) | TNK2IGF1RCYP3A4 | |
| SCHEMBL4363893 | 0.80 | TNK2 (1.00) | TNK2 | |
| SCHEMBL2459465 | 0.80 | IGF1R (0.78) | TNK2IGF1RCYP3A4 | |
| SCHEMBL400093 | 0.79 | IGF1R (0.64) | TNK2IGF1RCYP3A4 | |
| SCHEMBL4356232 | 0.79 | TNK2 (1.00) | TNK2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087395-A2 | UNSATURATED mTOR INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-08-02 | — | — | WO | disclosed |