Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.89 |
| ▸ | ITK | Q08881 | 5/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468488 | 0.94 | ADORA2A (1.00) | ADORA2AITKEHMT2TP53MMP13 | |
| SCHEMBL1470097 | 0.91 | ADORA2A (0.93) | ADORA2AITKEHMT2TP53MMP13 | |
| SCHEMBL1468370 | 0.91 | ADORA2A (1.00) | ADORA2AITKEHMT2TP53MMP13 | |
| SCHEMBL1468015 | 0.91 | ADORA2A (1.00) | ADORA2AITKEHMT2TP53MMP13 | |
| SCHEMBL1467942 | 0.89 | ADORA2A (1.00) | ADORA2AITK | |
| SCHEMBL12744869 | 0.89 | ADORA2A (0.86) | ADORA2AITKEHMT2TP53MMP13 | |
| SCHEMBL1468397 | 0.88 | ADORA2A (1.00) | ADORA2AITK | |
| SCHEMBL1468352 | 0.87 | ADORA2A (0.83) | ADORA2AITKEHMT2TP53MEN1 | |
| SCHEMBL8232572 | 0.87 | ADORA2A (0.69) | ADORA2AITKEHMT2EHMT1 | |
| SCHEMBL1468300 | 0.86 | ADORA2A (1.00) | ADORA2AITKEHMT2TP53MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |