Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711456 | 0.86 | GSK3B (0.73) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13711452 | 0.86 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8228618 | 0.86 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL1652648 | 0.83 | GSK3B (0.58) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87782 | 0.82 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8268075 | 0.82 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87832 | 0.81 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL81961 | 0.80 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL699220 | 0.80 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL698023 | 0.80 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |