⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21251413 | 0.90 | — | — | |
| SCHEMBL22756533 | 0.72 | — | — | |
| SCHEMBL4685343 | 0.65 | — | — | |
| SCHEMBL5539361 | 0.65 | — | — | |
| SCHEMBL21183384 | 0.62 | — | — | |
| SCHEMBL19594957 | 0.59 | — | — | |
| SCHEMBL15094440 | 0.57 | — | — | |
| SCHEMBL277574 | 0.57 | — | — | |
| SCHEMBL18943024 | 0.57 | — | — | |
| SCHEMBL23031136 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107543-A1 | INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-27 | — | — | WO | disclosed |