Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 13/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 1.00 |
| ▸ | FAP | Q12884 | 9/20 | 0.77 |
| ▸ | PREP | P48147 | 4/20 | 0.66 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232190 | 1.00 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL27193691 | 1.00 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL10309898 | 0.88 | DPP4 (0.79) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL12340742 | 0.87 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL21746927 | 0.87 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8231790 | 0.84 | DPP4 (0.72) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL15706014 | 0.83 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8286523 | 0.79 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL12343993 | 0.79 | DPP4 (0.68) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL15334846 | 0.79 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115577-A1 | SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-11 | — | — | US | disclosed |
| WO-2007100374-A9 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TUFTS COLLEGE (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007100374-A2 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240115577-A1 | SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES | DPP4, DPP7, ING2 | DPP4 1/4885DPP7 2/4885DPP8 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.