Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 16/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986255 | 0.92 | AVPR2 (0.58) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL8233642 | 0.92 | AVPR2 (0.60) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3977873 | 0.92 | AVPR2 (0.60) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3979687 | 0.92 | AVPR2 (0.60) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3983031 | 0.91 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL8227239 | 0.91 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL4493699 | 0.91 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3986162 | 0.91 | AVPR2 (0.61) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL8235953 | 0.91 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL8228940 | 0.91 | AVPR2 (0.57) | AVPR2AVPR1ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134862-A1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | BAYER HEALTHCARE AG (DE) | 2007-11-29 | — | — | WO | disclosed |