Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.82 |
| ▸ | PDE11A | Q9HCR9 | 14/20 | 0.82 |
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918587 | 0.93 | PDE4B (0.84) | PDE4BPDE11APDE10A | |
| SCHEMBL13918677 | 0.92 | PDE4B (0.83) | PDE4BPDE11APDE10A | |
| SCHEMBL8275107 | 0.90 | PDE4B (1.00) | PDE4BPDE11APDE10A | |
| SCHEMBL13918678 | 0.90 | PDE4B (0.82) | PDE4BPDE11APDE10A | |
| SCHEMBL13918685 | 0.90 | PDE4B (0.85) | PDE4BPDE11APDE10A | |
| SCHEMBL13918683 | 0.89 | PDE4B (0.90) | PDE4BPDE11APDE10A | |
| SCHEMBL13918765 | 0.89 | PDE4B (0.77) | PDE4BPDE11APDE10A | |
| SCHEMBL8274572 | 0.88 | PDE4B (0.81) | PDE4BPDE11APDE10A | |
| SCHEMBL8275114 | 0.87 | PDE4B (0.79) | PDE4BPDE11APDE10A | |
| SCHEMBL13918539 | 0.87 | PDE4B (0.79) | PDE4BPDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008327-A2 | XINAFOATE SALT OF A SUBSTITUTED 5-OXAZOL-2-YL-QUINOLINE COMPOUND | SCHERING CORPORATION (US) | 2008-01-17 | — | — | WO | disclosed |