Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBK | Q96KB5 | 2/20 | 1.00 |
| ▸ | AKT2 | P31751 | 3/20 | 0.57 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 6/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955342 | 0.82 | PBK (0.70) | PBKAKT2LRRK2GSK3BJAK3 | |
| SCHEMBL8229325 | 0.82 | PBK (1.00) | PBKAKT2NUDT1GSK3BJAK3 | |
| SCHEMBL2105753 | 0.79 | PBK (0.65) | PBKLRRK2JAK3JAK2JAK1 | |
| SCHEMBL29869963 | 0.77 | PBK (0.70) | PBKAKT2DOT1L | |
| SCHEMBL12605440 | 0.77 | AKT2 (0.70) | PBKAKT2NUDT1GSK3BJAK3 | |
| SCHEMBL7851332 | 0.76 | PBK (0.60) | PBKLRRK2JAK3JAK2JAK1 | |
| SCHEMBL12696600 | 0.75 | PBK (0.60) | PBKAKT2JAK2JAK1DOT1L | |
| SCHEMBL15421894 | 0.75 | PBK (0.60) | PBKAKT2JAK2JAK1DOT1L | |
| SCHEMBL15422005 | 0.75 | PBK (0.60) | PBKAKT2JAK2JAK1DOT1L | |
| SCHEMBL12605530 | 0.75 | AKT2 (0.68) | PBKAKT2NUDT1GSK3BJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002772-A1 | IMIDAZOPYRIDINE DERIVATIVES AND PBK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-01-06 | — | — | WO | disclosed |