Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240639 | 0.92 | HDAC1 (0.46) | HDAC1KCNH2CKS1BSKP1SKP2 | |
| SCHEMBL5317113 | 0.88 | HDAC1 (0.51) | HDAC1KCNH2BRD4TTK | |
| SCHEMBL14182612 | 0.86 | HDAC1 (0.49) | HDAC1KCNH2CKS1BSKP1SKP2 | |
| SCHEMBL5317952 | 0.85 | HDAC1 (0.63) | HDAC1KCNH2 | |
| SCHEMBL5318030 | 0.81 | HDAC1 (0.51) | HDAC1KCNH2BRD4TTK | |
| SCHEMBL3621805 | 0.80 | HDAC1 (0.67) | HDAC1KCNH2 | |
| SCHEMBL12841911 | 0.79 | HDAC1 (0.54) | HDAC1KCNH2 | |
| SCHEMBL8261906 | 0.78 | HDAC1 (0.49) | HDAC1KCNH2CKS1BSKP1SKP2 | |
| SCHEMBL8239914 | 0.78 | HDAC1 (0.62) | HDAC1KCNH2 | |
| SCHEMBL3610270 | 0.78 | HDAC1 (0.45) | HDAC1KCNH2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071961-A1 | BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |