Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 8/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15578107 | 0.86 | IL2 (0.48) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL8227596 | 0.86 | IL2 (0.44) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL15578292 | 0.84 | IL2 (0.47) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL15578356 | 0.83 | IL2 (0.46) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL15578373 | 0.81 | HTT (0.51) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL5033824 | 0.81 | IL2 (0.47) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL8233602 | 0.80 | IL2 (0.48) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL8227593 | 0.80 | MEN1 (0.54) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL15578350 | 0.78 | IL2 (0.48) | IL2TNFSTIM1ORAI1MEN1 | |
| SCHEMBL15578070 | 0.78 | IL2 (0.48) | IL2TNFSTIM1ORAI1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087429-A2 | PHENYL AND PYRIDYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |