Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901758 | 0.88 | GRM2 (0.55) | TAAR1GRM2AOC3HTR2A | |
| SCHEMBL2901760 | 0.88 | GRM2 (0.55) | TAAR1GRM2AOC3HTR2A | |
| SCHEMBL13086451 | 0.80 | GRM2 (0.51) | GRM2AOC3HTR2ALTA4H | |
| SCHEMBL2901376 | 0.78 | GRM2 (0.53) | GRM2AOC3HTR2ALTA4H | |
| SCHEMBL2896650 | 0.78 | GRM2 (0.53) | GRM2AOC3HTR2ALTA4H | |
| SCHEMBL2899321 | 0.78 | GRM2 (0.67) | GRM2HTR2A | |
| SCHEMBL2900047 | 0.78 | GRM2 (0.67) | GRM2HTR2A | |
| SCHEMBL19496621 | 0.75 | TAAR1 (0.70) | TAAR1AOC3HTR7HRH3 | |
| SCHEMBL2896644 | 0.74 | GRM2 (0.53) | GRM2AOC3HTR2ALTA4H | |
| SCHEMBL2896643 | 0.74 | GRM2 (0.53) | GRM2AOC3HTR2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007078523-A2 | 5-PHENYL-3-BENZYL-0XAZ0LIDIN-2-0NE DERIVATIVES AND RELATED COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ASTRAZENECA AB (SE) | 2007-07-12 | — | — | WO | disclosed |