Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 19/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 5/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294294 | 0.87 | NR3C2 (0.78) | NR3C2NR3C1PGRAR | |
| SCHEMBL4288195 | 0.86 | NR3C2 (0.64) | NR3C2NR3C1PGRAR | |
| SCHEMBL4291403 | 0.85 | NR3C2 (0.78) | NR3C2NR3C1PGRARMAPT | |
| SCHEMBL4302060 | 0.85 | NR3C2 (0.75) | NR3C2NR3C1PGRAR | |
| SCHEMBL4291105 | 0.85 | NR3C2 (0.75) | NR3C2NR3C1PGRAR | |
| SCHEMBL4289194 | 0.85 | NR3C2 (0.75) | NR3C2NR3C1PGRARMAPT | |
| SCHEMBL4298363 | 0.83 | NR3C2 (1.00) | NR3C2NR3C1PGRAR | |
| SCHEMBL4295732 | 0.82 | NR3C2 (0.71) | NR3C2NR3C1PGRARMAPT | |
| SCHEMBL4288624 | 0.80 | NR3C2 (0.72) | NR3C2NR3C1PGR | |
| SCHEMBL4293804 | 0.79 | NR3C2 (0.73) | NR3C2NR3C1PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |