Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230730 | 0.89 | DPP4 (0.94) | DPP4KCNH2MAPK1 | |
| SCHEMBL4229303 | 0.87 | DPP4 (1.00) | DPP4KCNH2 | |
| Trifluoroacetic Acid SCHEMBL5719515 | 0.79 | DPP4 (0.60) | DPP4KCNH2MAPK1 | |
| SCHEMBL8237707 | 0.77 | DPP4 (0.76) | DPP4KCNH2 | |
| SCHEMBL4221514 | 0.77 | DPP4 (1.00) | DPP4KCNH2 | |
| SCHEMBL4221509 | 0.77 | DPP4 (1.00) | DPP4KCNH2 | |
| SCHEMBL4220198 | 0.76 | DPP4 (1.00) | DPP4KCNH2 | |
| SCHEMBL4225076 | 0.76 | DPP4 (0.79) | DPP4KCNH2MAPK1 | |
| SCHEMBL8236794 | 0.75 | DPP4 (0.80) | DPP4KCNH2 | |
| Hydrochloric Acid SCHEMBL4226150 | 0.74 | DPP4 (0.79) | DPP4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |