Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.80 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530240 | 0.93 | BCHE (0.83) | BCHEWNK1RAB9APOLBTDP1 | |
| SCHEMBL8237823 | 0.88 | BCHE (0.65) | BCHEWNK1RAB9APOLBTDP1 | |
| SCHEMBL14437452 | 0.81 | KMT2A (0.69) | BCHEWNK1RAB9APOLBTDP1 | |
| SCHEMBL5527489 | 0.80 | ACACB (0.79) | BCHEWNK1POLBTDP1KDM4E | |
| SCHEMBL5534950 | 0.80 | KDM4E (0.89) | BCHERAB9APOLBTDP1KDM4E | |
| SCHEMBL5532737 | 0.79 | KMT2A (0.74) | BCHEWNK1RAB9APOLBTDP1 | |
| SCHEMBL8240361 | 0.78 | DHODH (0.70) | RAB9APOLBKDM4EALDH1A1LMNA | |
| SCHEMBL8237905 | 0.77 | KMT2A (0.84) | BCHERAB9APOLBTDP1KDM4E | |
| SCHEMBL28206921 | 0.75 | KDM4E (0.92) | BCHEWNK1RAB9APOLBTDP1 | |
| SCHEMBL5529559 | 0.74 | KMT2A (0.83) | RAB9APOLBTDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |