Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 19/20 | 0.77 |
| ▸ | GRM4 | Q14833 | 19/20 | 0.77 |
| ▸ | GRM6 | O15303 | 12/20 | 0.76 |
| ▸ | GRM7 | Q14831 | 7/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346142 | 0.87 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000472 | 0.86 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL21433290 | 0.86 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL4091094 | 0.86 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL8240833 | 0.83 | GRM4 (0.71) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL8237844 | 0.82 | GRM8 (0.73) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL8241144 | 0.81 | GRM8 (0.71) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000473 | 0.81 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL8240828 | 0.78 | GRM8 (0.83) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10027421 | 0.77 | GRM4 (1.00) | GRM8GRM4GRM6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |