Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401704 | 0.81 | HDAC1 (0.89) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL211677 | 0.80 | HDAC1 (0.76) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL16080083 | 0.80 | HDAC1 (0.56) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL3762348 | 0.79 | HDAC1 (0.64) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL20194281 | 0.79 | HDAC1 (0.62) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL8403312 | 0.79 | HDAC1 (0.79) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL8230897 | 0.77 | HDAC1 (0.52) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL8236773 | 0.76 | HDAC1 (0.51) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL1060598 | 0.76 | HDAC1 (0.79) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| Dinaline SCHEMBL29354254 | 0.76 | HDAC1 (0.79) | HDAC1HDAC2HDAC3MAPK1NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084390-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2007-07-26 | — | — | WO | disclosed |