Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498151 | 0.90 | BACE1 (0.84) | BACE1CTSD | |
| SCHEMBL4700639 | 0.88 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL4702990 | 0.86 | BACE1 (0.87) | BACE1CTSD | |
| SCHEMBL4702996 | 0.86 | BACE1 (0.87) | BACE1CTSD | |
| SCHEMBL4697559 | 0.86 | BACE1 (0.87) | BACE1CTSD | |
| SCHEMBL4698668 | 0.82 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL8240129 | 0.77 | BACE1 (0.78) | BACE1CTSD | |
| SCHEMBL5579116 | 0.76 | BACE1 (0.84) | BACE1CTSD | |
| SCHEMBL8240758 | 0.75 | BACE1 (0.84) | BACE1CTSD | |
| SCHEMBL4699445 | 0.74 | BACE1 (1.00) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047306-A1 | METHODS OF TREATING AMYLOIDOSIS USING ARYL-CYCLOPROPYL DERIVATIVE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |