SCHEMBL8240309

SCHEMBL8240309

Nc1nccn2c(C3CCC3)nc(-c3ccc(Cl)cc3)c12

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4352001 0.93 TNK2 (1.00) TNK2
SCHEMBL4361831 0.88 TNK2 (0.87) TNK2
SCHEMBL1129098 0.88 TNK2 (0.72) TNK2
SCHEMBL2462683 0.88 TNK2 (0.83) TNK2
SCHEMBL8230961 0.86 IGF1R (0.77) TNK2
SCHEMBL16748874 0.85 TNK2 (0.83) TNK2
SCHEMBL4356232 0.84 TNK2 (1.00) TNK2
SCHEMBL4354308 0.84 TNK2 (1.00) TNK2
SCHEMBL23803926 0.83 TNK2 (0.67) TNK2
SCHEMBL1128992 0.83 TNK2 (1.00) TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007087395-A2 UNSATURATED mTOR INHIBITORS OSI PHARMACEUTICALS, INC. (US) 2007-08-02 WO disclosed