Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038689 | 0.89 | PDE5A (0.61) | PDE5AKCNH2 | |
| SCHEMBL12768599 | 0.88 | PDE5A (0.64) | PDE5AKCNH2 | |
| SCHEMBL8234630 | 0.82 | PDE5A (0.86) | PDE5AKCNH2 | |
| SCHEMBL12768816 | 0.82 | PDE5A (0.58) | PDE5AKCNH2 | |
| SCHEMBL4045737 | 0.82 | PDE5A (0.58) | PDE5AKCNH2 | |
| SCHEMBL13815834 | 0.82 | PDE5A (0.75) | PDE5AKCNH2 | |
| SCHEMBL8242978 | 0.81 | PDE5A (0.74) | PDE5AKCNH2 | |
| SCHEMBL4040505 | 0.80 | PDE5A (0.57) | PDE5AKCNH2 | |
| SCHEMBL1527784 | 0.80 | PDE5A (0.72) | PDE5AKCNH2 | |
| SCHEMBL12768669 | 0.79 | PDE5A (0.43) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054778-A1 | PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)DERIVATIVE USED AS PDE5 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2007-05-18 | — | — | WO | disclosed |