SCHEMBL8240752

SCHEMBL8240752

CC(C)C[C@@H](I)NC(=O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CTSK P43235 7/20 0.51
CTSL P07711 2/20 0.51
CTSS P25774 2/20 0.51
CTSB P07858 1/20 0.51
CYP2D6 P10635 1/20 0.45
CAPN1 P07384 1/20 0.45
AAK1 Q2M2I8 2/20 0.41
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3499718 0.81 CA1 (0.54) CA1CA2CA7CTSKCTSL
SCHEMBL10800638 0.81 CA1 (0.54) CA1CA2CA7CTSKCTSL
SCHEMBL19227630 0.81 CA1 (0.58) CA1CA2CA7CTSKCTSL
SCHEMBL902049 0.81 CA1 (0.58) CA1CA2CA7CTSKCTSL
SCHEMBL19021911 0.81 CA1 (0.58) CA1CA2CA7CTSKCTSL
SCHEMBL8268764 0.81 CA1 (0.49) CA1CA2CA7CTSKCTSL
SCHEMBL4597828 0.81 CA1 (0.58) CA1CA2CA7CTSKCTSL
SCHEMBL19790304 0.80 CA1 (0.53) CA1CA2CA7CTSKCTSL
SCHEMBL14923535 0.80 CA1 (0.53) CA1CA2CA7CTSKCTSL
SCHEMBL25465070 0.79 CA1 (0.61) CA1CA2CA7CTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007075524-A2 SUBSTITUTED PIPERIDINES AS CALCIUM CHANNEL BLOCKERS MERCK & CO., INC. (US) 2007-07-05 WO disclosed