SCHEMBL8242594

SCHEMBL8242594

CN(C)C[C@]1(c2ccc(Cl)c(Cl)c2)CCCCC1CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 20/20 1.00
SLC6A3 Q01959 20/20 1.00
SLC6A2 P23975 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21726291 1.00 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL3523688 1.00 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL13253820 1.00 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL3523690 1.00 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL13253814 1.00 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL14430281 1.00 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL3517179 0.85 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL3517177 0.85 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL5137832 0.85 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
SCHEMBL3518464 0.85 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9868718-B2 Cycloalkylamines as monoamine reuptake inhibitors SUNOVION PHARMACEUTICALS INC. (US) 2018-01-16 US disclosed
WO-2007081857-A2 CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS SEPRACOR INC. (US) 2007-07-19 WO disclosed