Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768982 | 0.94 | PDE5A (0.68) | PDE5AKCNH2 | |
| SCHEMBL5247562 | 0.90 | PDE5A (0.57) | PDE5AKCNH2 | |
| SCHEMBL8241081 | 0.85 | PDE5A (0.55) | PDE5AKCNH2 | |
| SCHEMBL4041647 | 0.84 | PDE5A (0.66) | PDE5AKCNH2 | |
| SCHEMBL8240712 | 0.82 | PDE5A (0.57) | PDE5AKCNH2 | |
| SCHEMBL8243322 | 0.81 | PDE5A (0.58) | PDE5AKCNH2 | |
| SCHEMBL4218212 | 0.81 | PDE5A (0.68) | PDE5AKCNH2 | |
| SCHEMBL12768986 | 0.81 | PDE5A (0.68) | PDE5AKCNH2 | |
| SCHEMBL13805635 | 0.81 | PDE5A (0.68) | PDE5AKCNH2 | |
| SCHEMBL5245831 | 0.79 | PDE5A (0.60) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054778-A1 | PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)DERIVATIVE USED AS PDE5 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2007-05-18 | — | — | WO | disclosed |