SCHEMBL8243796

SCHEMBL8243796

O=C(C1CCCCCC1)N1CCCC1c1nnn(-c2cc(Cl)cc(Cl)c2)n1

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CPT1A P50416 3/20 0.46
GRM5 P41594 4/20 0.42
CPT2 P23786 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8248272 0.89 GRM5 (0.51) CPT1AGRM5
SCHEMBL8238657 0.88 GRM5 (0.52) CPT1AGRM5
SCHEMBL5303640 0.87 CPT1A (0.52) CPT1AGRM5CPT2
SCHEMBL5304397 0.86 CPT1A (0.53) CPT1AGRM5CPT2
SCHEMBL8247584 0.85 CPT1A (0.48) CPT1AGRM5CPT2
SCHEMBL5331792 0.85 GRM5 (0.53) CPT1AGRM5CPT2
SCHEMBL5331799 0.85 GRM5 (0.53) CPT1AGRM5CPT2
SCHEMBL8244984 0.83 CPT1A (0.51) CPT1AGRM5CPT2
SCHEMBL8247555 0.82 GRM5 (0.52) CPT1AGRM5
SCHEMBL8247582 0.79 CPT1A (0.51) CPT1ACPT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007039782-A1 TETRAZOLE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS Richter Gedeon Vegyészeti Gyár Rt. (HU) 2007-04-12 WO disclosed