Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1880494 | 0.82 | NOTUM (0.63) | NOTUMHPGDSMN1; SMN2CYP1A2GABRA2 | |
| SCHEMBL1890673 | 0.81 | NOTUM (0.54) | NOTUMHPGDSMN1; SMN2CYP1A2GABRA2 | |
| SCHEMBL12191258 | 0.78 | NOTUM (0.67) | NOTUMHPGDSMN1; SMN2CYP1A2GABRA2 | |
| SCHEMBL1878934 | 0.77 | NOTUM (0.63) | NOTUMCYP1A2GABRA2GABRB2KMT2A | |
| SCHEMBL9827734 | 0.77 | NOTUM (0.73) | NOTUMSMN1; SMN2CYP1A2GABRA2GABRB2 | |
| SCHEMBL9464564 | 0.77 | NOTUM (0.66) | NOTUMHPGDSMN1; SMN2CYP1A2GABRA2 | |
| Hydrochloric Acid SCHEMBL1878932 | 0.76 | NOTUM (0.62) | NOTUMCYP1A2GABRA2GABRB2KMT2A | |
| SCHEMBL9464637 | 0.76 | NOTUM (0.65) | NOTUMHPGDSMN1; SMN2CYP1A2GABRA2 | |
| SCHEMBL1881082 | 0.76 | NOTUM (0.65) | NOTUMSMN1; SMN2CYP1A2GABRA2GABRB2 | |
| SCHEMBL12214546 | 0.76 | NOTUM (0.65) | NOTUMHPGDSMN1; SMN2CYP1A2GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042545-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA-A RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2007-04-19 | — | — | WO | disclosed |