Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329845 | 0.85 | GRM5 (0.61) | GRM5 | |
| SCHEMBL4343688 | 0.82 | GRM5 (0.71) | GRM5 | |
| SCHEMBL4331867 | 0.81 | GRM5 (0.62) | GRM5 | |
| SCHEMBL8244741 | 0.81 | CYP2C19 (0.46) | GRM5 | |
| SCHEMBL4334637 | 0.77 | GRM5 (0.51) | GRM5 | |
| SCHEMBL4325876 | 0.76 | GRM5 (1.00) | GRM5 | |
| SCHEMBL4343710 | 0.72 | GRM5 (0.71) | GRM5 | |
| SCHEMBL4339145 | 0.72 | GRM5 (0.71) | GRM5 | |
| SCHEMBL4328445 | 0.72 | GRM5 (0.71) | GRM5 | |
| SCHEMBL4321100 | 0.72 | GRM5 (0.71) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023290-A1 | TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-03-01 | — | — | WO | disclosed |