Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562018 | 0.83 | KDM5A (0.61) | KDM5AEGFRALDH1A1MAPTKDM4E | |
| SCHEMBL5464068 | 0.79 | CYP3A4 (0.53) | KDM5AEGFRALDH1A1MAPTKDM4E | |
| SCHEMBL9423674 | 0.79 | KDM5A (0.58) | KDM5AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL31270677 | 0.79 | KDM5A (0.58) | KDM5AEGFRALDH1A1MAPTKDM4E | |
| SCHEMBL14532525 | 0.79 | KDM5A (0.58) | KDM5APOLBHPGDHSD17B10MEN1 | |
| SCHEMBL28620707 | 0.79 | KDM5A (0.55) | KDM5AEGFRALDH1A1MAPTKDM4E | |
| SCHEMBL10914822 | 0.76 | KDM5A (1.00) | KDM5AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL14540950 | 0.75 | KDM5A (0.44) | KDM5AEGFRALDH1A1MAPTKDM4E | |
| SCHEMBL9005854 | 0.75 | KDM5A (0.44) | KDM5AEGFRALDH1A1MAPTKDM4E | |
| SCHEMBL31270962 | 0.75 | KDM5A (0.49) | KDM5APTGS2CYP1A2CYP2C19ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022638-A1 | BENZODIAZEPINE AND BENZOPIPERAZINE ANALOG INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-03-01 | — | — | WO | disclosed |