Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.70 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.58 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 14/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247380 | 0.95 | EGLN3 (0.74) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL8245512 | 0.91 | EGLN3 (0.65) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL8247226 | 0.90 | EGLN3 (0.85) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL8247316 | 0.89 | EGLN3 (0.74) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL5335254 | 0.87 | EGLN3 (0.65) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL5311749 | 0.86 | EGLN3 (0.72) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL8244524 | 0.85 | EGLN3 (0.62) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL8245211 | 0.85 | EGLN3 (0.70) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL5311732 | 0.84 | EGLN3 (0.69) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL8248114 | 0.84 | EGLN1 (0.76) | EGLN3EGLN1EGLN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |